Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Mlekusch, W; Tillian, M; Lamprecht, M; Oettl, K; Krainz, H; Reibnegger, G.
The life-shortening effect of reduced physical activity is abolished by a fat rich diet.
Mech Ageing Dev. 1998; 105(1-2):61-73
Doi: 10.1016/S0047-6374(98)00080-3
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- Co-Autor*innen der Med Uni Graz
- Öttl Karl
- Reibnegger Gilbert
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- Abstract:
- In female mice on a control diet (3.6% fat) reduced physical activity leads to a reduction of the average life span. So the average age at death of an inactive group is 500 +/- 166 compared to 565 +/- 175 days in an active control group. If the animals are kept on a fat rich diet (12.4% fat) this effect of physical activity restriction is no longer observable and the average age at death is 570 +/- 142 days, within the range of the control animals. The increased fat intake seems to reduce the stress or to increase the resistance to stress in the activity restricted animals. So stress is a crucial determinant of life span.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Body Weight -
- Dietary Fats - metabolism
- Eating - metabolism
- Female - metabolism
- Incidence - metabolism
- Longevity - metabolism
- Mice - metabolism
- Neoplasms - epidemiology
- Organ Size - epidemiology
- Physical Conditioning, Animal - physiology
- Find related publications in this database (Keywords)
- Mice
- Mobility Restriction
- Fat Diet
- Longevity
- Stress