Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Mlekusch, W; Tillian, H; Lamprecht, M; Trutnovsky, H; Horejsi, R; Reibnegger, G.
The effect of reduced physical activity on longevity of mice.
Mech Ageing Dev. 1996; 88(3):159-168
Doi: 10.1016/0047-6374(96)01734-4
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- Co-Autor*innen der Med Uni Graz
- Horejsi Renate
- Reibnegger Gilbert
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- Abstract:
- Reduced physical activity leads, in female mice, to a reduction of the average and maximal life span. The average age at death of the inactive experimental group was 497 +/- 121 days (mean +/- S.D.) compared to 557 +/- 139 days in the active control group, and the six oldest inactive experimental mice died at age 732 +/- 50 days, while the six oldest active control mice died at 890 +/- 52 days. The restriction of mobility was connected with a higher growth rate and a higher body weight in spite of a significant decrease in food intake. In spite of a reduced food intake leading to a reduced whole body metabolism, the results show that mobility restriction shortens life span in female mice.
- Find related publications in this database (using NLM MeSH Indexing)
- Analysis of Variance -
- Animals -
- Body Weight - physiology
- Eating - physiology
- Female - physiology
- Longevity - physiology
- Mice - physiology
- Mice, Inbred Strains - physiology
- Motor Activity - physiology
- Restraint, Physical - physiology
- Find related publications in this database (Keywords)
- Female Mice
- Mobility Restriction
- Longevity