Medizinische Universität Graz - Research portal
Selected Publication:
Fruhwald, FM; Eber, B; Schumacher, M; Zweiker, R; Watzinger, N; Klein, WW.
Syncope in dilated cardiomyopathy is a predictor of sudden cardiac death.
Cardiology. 1996; 87(3):177-180
Doi: 10.1159/000177083
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Fruhwald Friedrich
- Co-authors Med Uni Graz
- Schumacher Martin
- Watzinger Norbert
- Zweiker Robert
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- Abstract:
- Fifty percent of patients with dilated cardiomyopathy die within 5 years of diagnosis. Syncope is known to be a predictor of poor outcome in patients with advanced heart failure. To assess the risk of patients with dilated cardiomyopathy with a history of syncope during standard medical treatment we compared this group to similar patients without syncope. Twenty-three patients with angiographically proven dilated cardiomyopathy and syncope were followed prospectively and compared to 201 patients without history of syncope. All patients showed a left-ventricular ejection fraction of less than 45%. Both groups did not differ in left-ventricular ejection fraction at baseline (30 +/- 7% in the syncope group, 30 +/- 8% in the no syncope group). Mean follow-up was 2.6 years in the syncope group and 2.4 years in the no syncope group. At baseline, syncope patients used more often amiodarone (p < 0.04), while there was no statistically significant difference between the two groups regarding the intake of digitalis, diuretics and angiotensin-converting enzyme inhibitors. Twenty-six percent of patients in the syncope group and 20% in the no syncope group died during follow-up (non significant). The striking difference, however, was the type of death: 5 out of 6 patients in the syncope group died suddenly compared to 13 of 41 patients in the no syncope group (p < 0.025). Patients with dilated cardiomyopathy and a history of syncope are at high risk of sudden death.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Amiodarone - therapeutic use
- Anti-Arrhythmia Agents - therapeutic use
- Cardiomyopathy, Dilated - drug therapy
- Death, Sudden, Cardiac - etiology
- Female - etiology
- Humans - etiology
- Male - etiology
- Middle Aged - etiology
- Prognosis - etiology
- Prospective Studies - etiology
- Stroke Volume - etiology
- Syncope - etiology
- Ventricular Function, Left - etiology
- Find related publications in this database (Keywords)
- Syncope
- Cardiomyopathy
- Dilated