Medizinische Universität Graz - Research portal
Selected Publication:
Weger, M; Leitner, G; Zirm, B; Wittels, P; Sabin, B; Porta, S.
Simultaneous Alterations of Circulating Mg Subfractions and Liver Related Parameters During Stress in Human Probands
MAGNESIUM, BULL 1996 18: 7-11.
Web of Science
- Leading authors Med Uni Graz
- Weger Martin
- Co-authors Med Uni Graz
- Leitner Gerhard
- Porta Sepp
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- Abstract:
- Allegedly [1, 2] stress leads to Mg loss from heart and liver, which should result in changed levels of circulating Mg and - if the liver did really participate - perhaps also in altered levels of urea, cholesterol blood glucose and cholinesterase activity. This should be investigated by application of a series of ergometric and psychological stresses to 12 young officer pilot trainees of the Austrian Federal Army before and after an aerobatic flight. Thus we provided stressful situations of various duration, type and intensity. Their effect was checked by 6 blood samples after short-term stresses before the flight and 5 samples afterwards, whereby total, ionized and calculated bound magnesium values were determined in addition to the liver parameters mentioned above. Blood sampled in stressful situations after the aerobatics, showed significantly increased levels of ionized magnesium (under physical and psychological stress: p = 0.001) with a simultaneous decrease in the calculated bound fraction (under psychological stress: p = 0.001, under physical stress: p = 0.006). At the same time the levels of cholesterol (p = 0.008) and urea (p = 0.023) were lowered as was the activity of cholinesterase (p = 0.046). There are distinct stress induced alterations in the circulating subfractions of magnesium, which are accompanied by significant alterations of liver parameters in a direction, which can well be interpreted as an indication of restricted liver function.