Medizinische Universität Graz - Research portal
Selected Publication:
Pummer, K; Pürstner, P; Auner, HL; Stettner, H; Trummer, H; Penkoff, H; Rauchenwald, M.
Serum immunosuppressive acid protein predicts lymph node metastases in patients with renal cell carcinoma.
Br J Urol. 1994; 73(6):612-614
Doi: 10.1111/j.1464-410X.1994.tb07543.x
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PubMed
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- Leading authors Med Uni Graz
- Pummer Karl
- Co-authors Med Uni Graz
- Pürstner Peter
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- Abstract:
- OBJECTIVE: To evaluate the usefulness of serum immunosuppressive acid protein (IAP) as a marker for lymph node metastases in patients with renal cell carcinoma. PATIENTS AND METHODS: Serum IAP levels were studied in 73 patients with renal cell carcinoma, prior to therapy. Serum IAP levels were correlated with the clinical and the post-operative histopathological stage. A threshold value of 800 micrograms/ml was applied. RESULTS: Statistical analysis revealed a better correlation between IAP concentration and disease than with any other variable. Sensitivity and specificity were 94% and 84%, respectively, thus providing good positive (65%) and negative (98%) predictive values regarding lymph node involvement. CONCLUSION: Measuring serum IAP levels can be a valuable contribution to lymph node staging in patients with renal cell cancer. The choice of cut-off value of 800 micrograms/ml has yet to be supported by a larger series.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Aged, 80 and over -
- Carcinoma, Renal Cell - blood
- Female - blood
- Humans - blood
- Kidney Neoplasms - blood
- Lymphatic Metastasis - blood
- Male - blood
- Middle Aged - blood
- Neoplasm Proteins - blood
- Neoplasm Staging - blood
- Tumor Markers, Biological - blood
- Find related publications in this database (Keywords)
- Immunosuppressive Acid Protein
- Renal Cell Carcinoma
- Lymph Node Metastases