Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Windhager, R; Groszschmidt, K; Tsuboyama, T; Siegl, H; Heinzl, H; Seidl, G; Plenk, H.
Recorticalization after bifocal internal bone transport in the double-plated sheep femur.
J Orthop Res. 1996; 14(1):94-101
Doi: 10.1002/jor.1100140116
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- Führende Autor*innen der Med Uni Graz
- Windhager Reinhard
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- Abstract:
- Distraction osteogenesis and bone remodelling after the end of bone transport were investigated in one femur each of six adult male sheep. A newly designed internal distraction device was used. A custom-made osteosynthesis plate was fixed on the lateral side of the femur, and two transporting plates driven by a transcutaneously inserted screwdriver moved two bone cylinders simultaneously over a 40 mm defect. An additional plate was applied ventrally to stabilize the device. Bone transport was begun 2 weeks postoperatively at 1 mm/day at each transporting plate until they came into contact. New bone formation within the distraction gaps was evaluated by computed tomography scans and was quantified at 4 and 6 months by dual energy x-ray absorptiometry as well as histomorphometry on polyfluorochrome-labelled undecalcified ground sections and microradiographs. At 4 months, all distraction gaps were bridged by abundant newly formed bone trabeculae, which were reduced and condensed to cortex-like layers of new bone at 6 months. Less new bone was always found under the lateral device than in the unplated medical and dorsal segments, but the amount of new bone under the ventral plate was comparable with that in the unplated regions. The results of this pilot study show that distraction osteogenesis can be achieved with an internal device such as this one and that recorticalization and restoration of a medullary canal occur despite the relatively rigid internal stabilization by the plates.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Bone Density -
- Bone Plates -
- Bone Remodeling -
- Equipment Design -
- Femur - pathology
- Follow-Up Studies - pathology
- Male - pathology
- Orthopedic Equipment - pathology
- Osteogenesis - pathology
- Sheep - pathology