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Schoellnast, H; Brader, P; Oberdabernig, B; Pisail, B; Deutschmann, HA; Fritz, GA; Schaffler, G; Tillich, M.
High-concentration contrast media in multiphasic abdominal multidetector-row computed tomography: effect of increased iodine flow rate on parenchymal and vascular enhancement.
J Comput Assist Tomogr. 2005; 29(5):582-587 Doi: 10.1097/01.rct.0000175502.79954.96
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Leading authors Med Uni Graz
Schoellnast Helmut
Co-authors Med Uni Graz
Bisail Borjana
Brader Peter
Deutschmann Hannes
Fritz Gerald
Schaffler Gottfried
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Abstract:
The purpose of this study was to assess the influence of the iodine flow rate on parenchymal and vascular enhancement during multiphasic abdominal multidetector-row computed tomography (MDCT). Fifteen patients underwent MDCT at an iodine flow rate of 1.2 g/s as well as 1.6 g/s (group A, protocols 1 and 2), and 90 patients underwent MDCT at an iodine flow rate of 1.2 g/s (group B) or 1.6 g/s (group C). Measurements were performed for all groups in the liver, spleen, pancreas, portal vein, inferior vena cava, and abdominal aorta. Aortal and pancreatic enhancement during the arterial phase was significantly higher with the higher iodine flow rate. The mean difference in aortal enhancement was 60 Hounsfield units (HU) between protocols 1 and 2 of group A, and the mean difference was 70 HU between groups B and C. The mean difference in pancreatic enhancement was 10 HU between protocols 1 and 2 of group A and 17 HU between groups B and C. During the portal and hepatic venous phases, no significant difference in enhancement was observed. A high iodine flow rate in multiphasic abdominal MDCT improves enhancement of the aorta and the pancreas during the arterial phase but does not influence later phases.
Find related publications in this database (using NLM MeSH Indexing)
Abdomen - blood supply
Aged -
Contrast Media - administration & dosage Contrast Media - pharmacokinetics
Female -
Humans -
Image Processing, Computer-Assisted -
Injections, Intravenous -
Iohexol - administration & dosage Iohexol - analogs & derivatives Iohexol - pharmacokinetics
Iopamidol - administration & dosage Iopamidol - analogs & derivatives Iopamidol - pharmacokinetics
Male -
Middle Aged -
Radiography, Abdominal -
Retrospective Studies -
Statistics, Nonparametric -
Tomography, X-Ray Computed - methods

Find related publications in this database (Keywords)
abdominal multidetector-row computed tomography
iodine flow rate
parenchymal enhancement
vascular enhancement
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