Gewählte Publikation:
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Neuro
Krebs
Kardio
Lipid
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Microb
Legat, FJ; Krause, R; Zenahlik, P; Hoffmann, C; Scholz, S; Salmhofer, W; Tscherpel, J; Tscherpel, T; Kerl, H; Dittrich, P.
Penetration of piperacillin and tazobactam into inflamed soft tissue of patients with diabetic foot infection.
Antimicrob Agents Chemother. 2005; 49(10):4368-4371
Doi: 10.1128/AAC.49.10.4368-4371.2005
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- Führende Autor*innen der Med Uni Graz
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Legat Franz
- Co-Autor*innen der Med Uni Graz
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Kerl Helmut
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Krause Robert
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Salmhofer Wolfgang
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- Abstract:
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We investigated the pharmacokinetics of piperacillin and tazobactam in the extracellular space fluid of inflamed soft tissues of six patients with diabetic foot infection using in vivo microdialysis and found similar penetration for piperacillin but not for tazobactam into inflamed and noninflamed soft tissue.
- Find related publications in this database (using NLM MeSH Indexing)
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Aged -
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Aged, 80 and over -
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Anti-Bacterial Agents - pharmacokinetics
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Anti-Bacterial Agents - therapeutic use
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Area Under Curve -
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Diabetic Foot - metabolism
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Extracellular Fluid - metabolism
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Female -
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Humans -
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Inflammation - microbiology
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Inflammation - pathology
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Male -
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Microdialysis -
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Middle Aged -
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Penicillanic Acid - analogs & derivatives
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Penicillanic Acid - pharmacokinetics
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Penicillanic Acid - therapeutic use
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Piperacillin - pharmacokinetics
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Piperacillin - therapeutic use
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Soft Tissue Infections - metabolism