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SHR Neuro Krebs Kardio Lipid Stoffw Microb

Legat, FJ; Krause, R; Zenahlik, P; Hoffmann, C; Scholz, S; Salmhofer, W; Tscherpel, J; Tscherpel, T; Kerl, H; Dittrich, P.
Penetration of piperacillin and tazobactam into inflamed soft tissue of patients with diabetic foot infection.
Antimicrob Agents Chemother. 2005; 49(10):4368-4371 Doi: 10.1128/AAC.49.10.4368-4371.2005 [OPEN ACCESS]
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Führende Autor*innen der Med Uni Graz
Legat Franz
Co-Autor*innen der Med Uni Graz
Kerl Helmut
Krause Robert
Salmhofer Wolfgang
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Abstract:
We investigated the pharmacokinetics of piperacillin and tazobactam in the extracellular space fluid of inflamed soft tissues of six patients with diabetic foot infection using in vivo microdialysis and found similar penetration for piperacillin but not for tazobactam into inflamed and noninflamed soft tissue.
Find related publications in this database (using NLM MeSH Indexing)
Aged -
Aged, 80 and over -
Anti-Bacterial Agents - pharmacokinetics
Anti-Bacterial Agents - therapeutic use
Area Under Curve -
Diabetic Foot - metabolism
Extracellular Fluid - metabolism
Female -
Humans -
Inflammation - microbiology
Inflammation - pathology
Male -
Microdialysis -
Middle Aged -
Penicillanic Acid - analogs & derivatives
Penicillanic Acid - pharmacokinetics
Penicillanic Acid - therapeutic use
Piperacillin - pharmacokinetics
Piperacillin - therapeutic use
Soft Tissue Infections - metabolism

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