Medizinische Universität Graz - Research portal
Selected Publication:
Modl, M; Eber, E; Weinhandl, E; Gruber, W; Zach, MS.
Reproducibility of forced expiratory flow and volume measurements in infants with bronchiolitis.
PEDIAT PULM 1999 28: 429-435.
Doi: 10.1002%2F%28SICI%291099-0496%28199912%2928%3A6%3C429%3A%3AAID-PPUL8%3E3.0.CO%3B2-3
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Modl Manfred
- Zach Maximilian
- Co-authors Med Uni Graz
- Eber Ernst
- Weinhandl Elisabeth
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- Abstract:
- The end-tidal rapid thoracoabdominal compression (ETRTC) technique is an established method for lung function testing in infancy. Previous work in healthy infants, however, has shown that measurements with the newly developed raised volume rapid thoracoabdominal compression (RVRTC) technique are more reproducible than those with the ETRTC technique. So far, reproducibility of the two techniques has not been compared in infants with acute airway disease. Twenty-three infants with acute viral bronchiolitis underwent lung function assessment with both the ETRTC and the RVRTC technique. A series of 8-10 measurements with each technique was done in randomized order. Forced expired volumes at 0.5, 0.75, and 1 sec after chest compression (FEV(0.5), FEV(0.75), and FEV(1.0)) were measured with the RVRTC technique; maximum expiratory flow at functional residual capacity (V'(maxFRC)) was measured with the ETRTC technique. Group mean intrasubject coefficients of variation (CV) were 4.84% for FEV(0.5), 5.01% for FEV(0.75), 5.43% for FEV(1. 0), and 13.79% for V'(maxFRC), respectively. Differences between FEV parameters were statistically insignificant, whereas the difference between each FEV parameter and V'(maxFRC) was highly significant (P < 0.001). In infants with acute viral bronchiolitis, RVRTC measurements have significantly less intraindividual variability than flow rates assessed with the conventional ETRTC technique. This finding provides the basis for assessing disease course and effects of therapeutic interventions on an individual basis. Copyright 1999 Wiley-Liss, Inc.
- Find related publications in this database (using NLM MeSH Indexing)
- Analysis of Variance -
- Bronchiolitis - diagnosis
- Female - diagnosis
- Forced Expiratory Flow Rates - diagnosis
- Forced Expiratory Volume - physiology
- Humans - physiology
- Infant - physiology
- Male - physiology
- Reproducibility of Results - physiology
- Sensitivity and Specificity - physiology
- Find related publications in this database (Keywords)
- Infant Lung Function
- Rapid Thoracoabdominal Compression
- Raised Lung Volume
- Reproducibility
- Wheezy Infants