Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Domej, W; Maier, A; Schmidt, F; Dimai, HP; Wirnsberger, GH.
Relapse of pulmonary Mycobacterium kansasii disease associated with large-cell cancer of the lung: a case report.
Oncol Rep. 1998; 5(4):853-856
Doi: 10.3892/or.5.4.853
(- Case Report)
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Domej Wolfgang
- Wirnsberger Gerhard
- Co-Autor*innen der Med Uni Graz
- Dimai Hans Peter
- Schmidt Ferdinand
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- Abstract:
- A 43-year-old caucasian male diabetic presented with purulent cough and a history of weight-loss, elevated temperature, night-sweat and dyspnea. Four years previously, the patient had undergone a 12-month antimycobacterial regimen because of pulmonary mycobacterium kansasii (MK) disease of the left upper lobe (LUL). Treatment had led to complete recovery with the exception of minor fibrous residuals in the involved pulmonary segments. Chest radiograph and computed tomography (CT), performed on recent admission, revealed a dense infiltration of these residual-containing segments. Microbiological evaluation of bronchial brushings, aspirates and histology of the transbronchial biopsies indicated a relapse of pulmonary MK disease. Although antimycobacterial treatment was started immediately, therapeutic effects were only minimal and remained to be limited to the initial phase of the treatment. After four weeks of treatment, the patient's general condition worsened again. Follow-up CT of the lung showed a marked increase of the infiltration in the left apicoposterior lobe and re-bronchoscopy showed a tumorous protrusion of the bronchial wall involving the apicoposterior segment ostium, a finding which was not seen in the previous bronchoscopy. Histology of the transbronchial biopsies revealed a carcinoma mainly from large-cell type.
- Find related publications in this database (using NLM MeSH Indexing)
- Carcinoma, Non-Small-Cell Lung - complications
- Diabetes Mellitus, Type 1 - complications
- Humans - complications
- Lung Diseases - complications
- Lung Neoplasms - complications
- Male - complications
- Middle Aged - complications
- Mycobacterium Infections, Atypical - complications
- Mycobacterium kansasii - complications
- Recurrence - complications
- Tomography, X-Ray Computed - complications
- Find related publications in this database (Keywords)
- Nontuberculous Mycobacteriosis
- Mycobacterium Kansasii
- Lung Cancer