Medizinische Universität Graz - Research portal
Selected Publication:
Olschewski, H; Seeger, W.
Pathophysiology of pulmonary hypertension
Z Kardiol. 1994; 83 Suppl 6:181-191
Web of Science
PubMed
- Leading authors Med Uni Graz
- Olschewski Horst
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- Abstract:
- Severe pulmonary hypertension has a poor prognosis and is complicated to treat. It is caused by states of hypoxia, thromboembolism, chronic inflammation, pulmonary venous congestion and/or hypercirculation. In the course of some days up to many years, remodelling of the pulmonary vasculature may occur. Morphologic characteristics of the remodelling process have extensively been described, while the underlying cellular and molecular mechanisms remain largely unknown. Increasing knowledge of the features of pulmonary vasoconstriction and vascular remodelling, will, however, improve the options for future therapy.
- Find related publications in this database (using NLM MeSH Indexing)
- Anoxia - etiology
- Endothelium, Vascular - physiopathology
- Feedback - physiology
- Humans - physiology
- Hypertension, Pulmonary - etiology
- Prognosis - etiology
- Pulmonary Artery - physiopathology
- Pulmonary Embolism - etiology
- Find related publications in this database (Keywords)
- PULMONARY HYPERTENSION
- LUNG VASCULAR REMODELING
- HYPOXIC PULMONARY VASOCONSTRICTION
- THROMBOEMBOLISM
- VASOACTIVE AGENTS
- GROWTH FACTORS
- ENDOTHELIN