Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Lang, U; Kunzel, W; Clark, KE.
Uterine perfusion and fetal growth
GYNAKOLOGE 1999 32: 354-359.
Doi: 10.1007/PL00003240
Web of Science
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- Führende Autor*innen der Med Uni Graz
- Lang Uwe
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- Abstract:
- An adequate increase of uterine blood flow throughout gestation is essential for uterine, placental and fetal growth. Maternal cardiovascular adaptation has to provide the uterine perfusion that is necessary to meet the requirements of the developing and growing fetus by providing transport of nutrients and oxygen to the placenta and the fetus. Thus uterine blood flow is inextricably linked to fetal growth and survival. Reductions of uterine blood flow can occur under acute or chronic conditions or in a combination of both. Chronic reductions of uterine blood flow can be observed in pregnancy induced hyertension (PIH), diabetes mellitus in pregnancy and intrauterine growth restriction (IUGR). Chronic restrictions in uterine blood flow will elicit a placental and fetal response in the form of growth adaptation to the reduced supply of oxygen and nutrients to the conceptus. If compensatory growth restriction reaches its limits intrauterine fetal distress can ensue.
- Find related publications in this database (Keywords)
- uterine blood flow
- fetal growth
- growth restriction
- experimental IUGR