Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Ruhswurm, I; Ries, E; Krepler, K; Derbolav, A; Rieger, A; Armbruster, C; Wedrich, A.
Control of cytomegalovirus retinitis after combination antiretroviral therapy.
ACTA OPHTHALMOL SCANDINAVICA 1999 77: 471-473.
Doi: 10.1034/j.1600-0420.1999.770425.x
(- Case Report)
Web of Science
PubMed
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FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Wedrich Andreas
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- Abstract:
- PURPOSE: To report on AIDS patients having combination antiretroviral therapy whose cytomegalovirus (CMV) retinitis remained inactive after discontinuation of anti-CMV maintenance therapy. METHODS: We describe the course of CMV-retinitis in 3 patients with AIDS after initiation of combination antiretroviral therapy. RESULTS: After cessation of anti-CMV therapy no relapse of CMV-retinitis has been observed for up to 18 months. Two of the patients developed new CMV-retinitis in the first months after initiation of combination therapy, nevertheless after further improvement of immunological parameters retinitis remained stable without anti-CMV therapy. CONCLUSION: The sustained immunological effects of combination therapy are possibly sufficient enough to provide protection against CMV-retinitis.
- Find related publications in this database (using NLM MeSH Indexing)
- AIDS-Related Opportunistic Infections - complications
- Adult - complications
- Anti-HIV Agents - therapeutic use
- CD4 Lymphocyte Count - therapeutic use
- Cytomegalovirus Retinitis - complications
- Drug Therapy, Combination - complications
- Follow-Up Studies - complications
- Ganciclovir - therapeutic use
- HIV - genetics
- Humans - genetics
- Indinavir - therapeutic use
- Male - therapeutic use
- Middle Aged - therapeutic use
- RNA, Viral - analysis
- Saquinavir - therapeutic use
- Find related publications in this database (Keywords)
- acquired immunodeficiency syndrome (AIDS)
- combination antiretroviral therapy cytomegalovirus (CMV) retinitis
- maintenance therapy