Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Krepler, K; Polska, E; Wedrich, A; Schmetterer, L.
Ocular blood flow parameters after pars plana vitrectomy in patients with diabetic retinopathy.
Retina. 2003; 23(2):192-196
Doi: 10.1097/00006982-200304000-00009
Web of Science
PubMed
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FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Wedrich Andreas
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- Abstract:
- Background: Whereas the anatomic result of vitrectomy in patients with vitreoretinal complications due to diabetes is usually satisfying, the functional outcome is sometimes poor. The authors investigated whether this may be related in part to effects of vitrectomy on ocular perfusion. Methods: Ocular hemodynamics were measured before vitrectomy and 1 and 4 weeks postoperatively in 13 consecutive diabetic patients. Pulsatile choroidal blood flow was assessed with laser interferometric measurement of fundus pulsation amplitude. In addition, mean blood flow velocity and resistive index in the ophthalmic artery, the central retinal artery, and the posterior ciliary arteries were measured with color Doppler imaging. Results: Fundus pulsation amplitude was significantly reduced after surgery as compared to baseline (baseline: 3.7 +/- 1.0 mum; 4 weeks: 3.1 +/- 0.8; P < 0.001). Postoperatively, mean blood flow velocity in the central retinal artery (P = 0.009) and the posterior ciliary arteries (P = 0.0006) was significantly reduced, whereas resistive index was increased in the central retinal artery (P = 0.028) but not in the posterior ciliary arteries. Conclusions: The current data suggest that vitrectomy induces significant reductions in ocular blood flow in patients with diabetic retinopathy. Whether this may affect the visual outcome after vitrectomy or whether this reflects improved retinal oxygenation after vitrectomy remains to be established.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Blood Flow Velocity -
- Diabetic Retinopathy - physiopathology
- Female -
- Humans -
- Intraocular Pressure - physiology
- Laser-Doppler Flowmetry -
- Male -
- Middle Aged -
- Prospective Studies -
- Regional Blood Flow -
- Retinal Artery - physiology
- Ultrasonography, Doppler, Color -
- Vitrectomy -
- Find related publications in this database (Keywords)
- blood flow
- diabetic retinopathy
- vitrectomy