Medizinische Universität Graz - Research portal
Selected Publication:
Lisborg, P; Jatzko, G; Horn, M; Neumann, HJ; Müller, M; Stettner, H; Denk, H.
Radical surgery (R2 resection) for gastric cancer. A multivariate analysis.
Scand J Gastroenterol. 1994; 29(11):1024-1028
Doi: 10.3109/00365529409094880
Web of Science
PubMed
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- Co-authors Med Uni Graz
- Denk Helmut
- Horn Michael
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- Abstract:
- BACKGROUND: Extended lymphadenectomy remains controversial in the Western world. Its evaluation and the identification of high-risk patients after surgery are important tasks. METHODS: A retrospective prognostic study of 318 patients treated for potential cure of gastric cancer was performed. All patients underwent extended lymphadenectomy. Clinical histopathologic and surgical factors were examined for their influence on survival by univariate and multivariate analysis. RESULTS: Postoperative mortality was 4.4% (14 of 318), and the 5-year adjusted survival rate was 57.8%. Multivariate analysis using the Cox model identified seven factors as having independent influence on survival. Detrimental factors were male gender, age over 65 years, high pN category, increasing number of lymph nodes invaded by metastases, total gastric resection, splenectomy, and increasing number of perioperatively required blood units. CONCLUSION: Extended lymphadenectomy was possible without sacrificing low postoperative mortality rates. The importance of certain prognostic factors, in particular lymph node status, could be confirmed.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Female -
- Gastrectomy - methods
- Humans - methods
- Lymph Node Excision - methods
- Male - methods
- Prognosis - methods
- Proportional Hazards Models - methods
- Retrospective Studies - methods
- Risk Factors - methods
- Splenectomy - methods
- Stomach Neoplasms - mortality
- Survival Analysis - mortality
- Survival Rate - mortality
- Time Factors - mortality
- Find related publications in this database (Keywords)
- Gastric Carcinoma
- Histologic Type
- Independent Prognostic Factors
- Lymph Node Metastases
- Splenectomy