Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Klein, M; Rosen, A; Lahousen, M; Graf, A; Vavra, N; Beck, A.
Radical lymphadenectomy in the primary carcinoma of the fallopian tube.
ARCH GYNECOL OBSTET. 1993; 253(1): 21-25.
Doi: 10.1007/BF02770629
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- Co-Autor*innen der Med Uni Graz
- Lahousen Manfred
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- Abstract:
- The primary carcinoma of the Fallopian tube is a highly aggressive tumor which can spread by the lymphatic route. The object of the present study was to evaluate the impact of radical pelvic and para-aortic lymphadenectomy on overall survival. Radical lymphadenectomy was performed on twelve patients in addition to hysterectomy and bilateral adnexectomy (group I). Twenty-eight patients subjected only to hysterectomy and adnexectomy formed the control group (group II). On average 47.6 lymph nodes were excised per patient. As long as the carcinoma was limited to adnexa and uterus (stages I and II), no lymph node metastases were found, only in stages III and IV were lymph node metastases detectable. Even though the median survival time of group I was considerably higher than of group II (43 versus 35 months), there was no statistically significant difference between the two groups (P < 0.65). Patients with stage III and stage IV disease had relatively longer median survival times if they had a lymphadenectomy. However, the difference was not statistically significant (P < 0.91). We cannot therefore recommend routine radical lymphadenectomy for primary Fallopian tube carcinoma. Whether or not lymph node dissection would lead to better results from rational selection of patient for adjuvant therapy is not known.
- Find related publications in this database (using NLM MeSH Indexing)
- Fallopian Tube Neoplasms - mortality
- Female - mortality
- Follow-Up Studies - mortality
- Humans - mortality
- Hysterectomy - mortality
- Lymph Node Excision - mortality
- Lymphatic Metastasis - mortality
- Neoplasm Staging - mortality
- Ovariectomy - mortality
- Survival Rate - mortality
- Find related publications in this database (Keywords)
- Fallopian Tube
- Carcinoma
- Lymphadenectomy