Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Groell, R; Kugler, C; Aschauer, M; Rienmueller, R; Stauber, R; Trauner, M; Mischinger, HJ.
Quantitative perfusion parameters of focal nodular hyperplasia and normal liver parenchyma as determined by electron beam tomography.
Br J Radiol. 1995; 68(815):1185-1189
Doi: 10.1259/0007-1285-68-815-1185
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- Führende Autor*innen der Med Uni Graz
- Groell Reinhard
- Co-Autor*innen der Med Uni Graz
- Aschauer Manuela
- Mischinger Hans-Jörg
- Rienmüller Rainer
- Stauber Rudolf
- Trauner Michael
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- Abstract:
- Eight patients with known focal nodular hyperplasia (FNH) were studied by electron beam tomography (EBT) in a multisection flow mode at defined time intervals after intravenous contrast agent injection. Various regions of interest (ROIs) were defined in the areas of FNH, normal liver parenchyma, aorta and portal vein. In each ROI density changes were measured and plotted against time. In those time-density curves (TDCs) the slope, the time of maximal enhancement and the absolute density value of peak enhancement were determined. Arterial tissue perfusion was calculated for normal liver parenchyma and FNH. In all eight patients significant differences in peak density (123.88 +/- 18.92 HU vs 102.5 +/- 15.49 HU, p = 0.012), in the rate of arterial contrast enhancement (252.63 +/- 28.05 HU min-1 vs 38.88 +/- 4.19 HU min-1, p = 0.012) and in the arterial tissue perfusion (1.36 +/- 0.19 ml min-1 cm-3 vs 0.21 +/- 0.03 ml min-1 cm-3, p = 0.012) between FNH and normal liver parenchyma were found. Perfusion values of normal liver parenchyma correspond to those determined by inert gas clearance. Further studies will determine the practicability of this quantitative method in the evaluation of global and other focal liver diseases.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Angiography -
- Female -
- Humans -
- Hyperplasia - radiography
- Liver - pathology Liver - radiography
- Liver Circulation -
- Middle Aged -
- Time Factors -
- Tomography -