Medizinische Universität Graz - Research portal
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SHR Neuro Cancer Cardio Lipid Metab Microb
Saha, S; Lang, A; von, der, Linden, J; Wassilowsky, D; Peterss, S; Pichlmaier, M; Hagl, C; Juchem, G; Joskowiak, D.
Clinical Results and Quality of Life after Nonelective Cardiac Surgery in Octogenarians.
Thorac Cardiovasc Surg. 2022; 70(5): 384-391.
Doi: 10.1055/s-0041-1730029
PubMed
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- Co-authors Med Uni Graz
- von der Linden Julia
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- Abstract:
- BACKGROUND: We analyzed the short-term and mid-term outcomes as well as the health-related quality of life (HRQOL) of octogenarians undergoing elective and urgent cardiac surgery. PATIENTS AND METHODS: We retrospectively identified 688 consecutive octogenarians who underwent cardiac surgery at our center between January 2012 and December 2019. A propensity score matching was performed which resulted in the formation of 80 matched pairs. The patients were interviewed and the Short Form-36 survey was used to assess the HRQOL of survivors. Multivariable analysis incorporated binary logistic regression using a forward stepwise (conditional) model. RESULTS: The median age of the matched cohort was 82 years (p = 0.937), among whom, 38.8% of patients were female (p = 0.196). The median EuroSCORE II of the matched cohort was 19.4% (10.1-39.1%). The duration of postoperative mechanical ventilation was found to be independently associated with in-hospital mortality (odds ratio: 1.01 [95% confidence interval: 1.0-1.02], p = 0.038). The survival rates at 1, 2, and 5 years was 75.0, 72.0, and 46.0%, respectively. There was no difference in the total survival between the groups (p = 0.080). The physical health summary score was 41 (30-51) for the elective patients and 42 (35-49) for the nonelective octogenarians (p = 0.581). The median mental health summary scores were 56 (48-60) and 58 (52-60), respectively (p = 0.351). CONCLUSION: Cardiac surgery can be performed in octogenarians with good results and survivors enjoy a good quality of life; however, the indication for surgery or especially for escalation of therapy should always be made prudently, reserved, and in consideration of patient expectations.
- Find related publications in this database (using NLM MeSH Indexing)
- Age Factors - administration & dosage
- Aged, 80 and over - administration & dosage
- Cardiac Surgical Procedures - adverse effects
- Female - administration & dosage
- Humans - administration & dosage
- Male - administration & dosage
- Octogenarians - administration & dosage
- Postoperative Complications - administration & dosage
- Quality of Life - administration & dosage
- Retrospective Studies - administration & dosage
- Risk Factors - administration & dosage
- Treatment Outcome - administration & dosage