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SHR Neuro Cancer Cardio Lipid Metab Microb

Hauer, AC; Sultan, M; Darma, A; Altamimi, E; Serban, DE; Assa, A; Franco, CPS; de, Ridder, L; Wilson, DC; Afzal, NA; Bronsky, J; Georgieva, M; Aloi, M; Urbonas, V; Navas-López, VM; Medina, JR; Turner, D; Amil-Dias, J.
Management of pediatric inflammatory bowel diseases in limited-resource settings: A position paper from the Paediatric IBD Porto Group of ESPGHAN.
J Pediatr Gastroenterol Nutr. 2025; Doi: 10.1002/jpn3.70121
Web of Science PubMed FullText FullText_MUG

Leading authors Med Uni Graz: Hauer Almuthe
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Abstract:: OBJECTIVE: Pediatric inflammatory bowel diseases (PIBDs), despite being more prevalent in westernized nations, show an increasing incidence worldwide. Accurate evaluation, diagnosis, therapy, and monitoring are mandatory for the adequate management of patients, as is a sensible use of expensive resources, which may be limited in some parts of the world. This limitation often poses challenges to diagnose and treat patients. As the long-term prognosis very much depends on early diagnosis and remission of active disease, it is important to consider reasonable alternatives that may help clinicians to act accordingly within resource constraints, without downgrading previously published guidelines. METHODS: A group of experts from the "Paediatric IBD Porto Group" of European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) as well as pediatric and adult IBD experts, trained in IBD centers and having working experience in limited-resource settings (LR settings), joined efforts to suggest alternative options in settings where resources are limited, while prioritizing an acceptable cost-effectiveness ratio. Almost all recently published ESPGHAN guidelines and position papers on PIBD were evaluated, and the writing group framed proposals for adaptation in situations with limited access to more expensive resources or tools. RESULTS: Ninety consensus-based recommendations, derived from the available evidence, were formulated. Diagnostic protocol, biochemical evaluation, imaging and endoscopy, monitoring and options for nutritional, medical and surgical treatment were addressed. Cooperation between professionals and institutions was suggested to improve quality of care and optimize use of available expertise. Patient education, counseling, mental health and transition of care were also addressed. CONCLUSION: Diagnosis and management of PIBD are complex and costly in medical resources, but some alternative protocols could provide acceptable results and help with accurate diagnosis and management. These recommendations and practice points may offer useful guidance in settings where resources may be limited while still providing good medical practice.
Find related publications in this database (Keywords): child; low-income countries; middle-income countries; pediatric