Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Bucerius, J; Joe, AY; Lindstaedt, I; Manka-Waluch, A; Reichmann, K; Ezziddin, S; Palmedo, H; Biersack, HJ.
Single- vs. dual-head SPECT for detection of myocardial ischemia and viability in a large study population
CLIN IMAG. 2007; 31(4): 228-233.
Doi: 10.1016/j.clinimag.2007.02.025
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Bucerius Jan Alexander
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- Abstract:
- Background: As single-head data acquisition for thallium-201 myocardial SPECT is a frequently used method mainly in the outpatient medical care as well as in smaller hospitals, comparison to dual-head data collection is a still discussed issue mainly with regard to quality control and -assurance. Methods: A total of 1334 patients undergoing thallium-201 myocardial SPECT for diagnosis of myocardial ischemia and/or viability have been retrospectively analyzed. In 554 patients, a single-head gamma camera (360 degrees rotation) has been applied, whereas a dual-head gamma camera (180 degrees rotation) has been used in 780 patients. Four hundred twenty-six patients received both myocardial SPECT as well as coronary angiography. The diagnostic value of both applied acquisition techniques has been analyzed. Results: Regarding myocardial viability, positive predictive value for the diagnosis of myocardial scar tissue was significantly higher for dual-head-as compared to single-head acquisition. Among the 426 patients undergoing diagnosis of myocardial ischemia, significant differences have only been found with regard to specificity being higher in the single-head acquisition. Diagnosis of myocardial ischemia related to a distinct myocardial perfusion region showed a significantly higher sensitivity of dual-head acquisition for the left anterior descending perfusion area, whereas specificity was significantly higher for single-head acquisition. Conclusions: Our results indicate a beneficial effect of dual-head data collection with regard to sensitivity of the diagnosis of myocardial ischemia. In contrast, single-head data acquisition was superior with regard to specificity. However, it is justified to preferably apply dual-head data collection in clinical routine due to the shorter acquisition time leading to an evident time benefit of this acquisition technique. (C) 2007 Elsevier Inc. All rights reserved.
- Find related publications in this database (Keywords)
- myocardial SPECT
- single-head
- dual-head
- myocardial ischemia
- myocardial viability