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Klaritsch, P; Reich, O; Giuliani, A; Tamussino, K; Haas, J; Winter, R.
Delivery outcome after cold-knife conization of the uterine cervix.
Gynecol Oncol. 2006; 103(2): 604-607.
Doi: 10.1016/j.ygyno.2006.04.003
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- Leading authors Med Uni Graz
- Klaritsch Philipp
- Co-authors Med Uni Graz
- Giuliani Albrecht
- Haas Josef
- Reich Olaf
- Tamussino Karl
- Winter Raimund
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- Abstract:
- OBJECTIVE: To estimate the risk for preterm delivery and obstetric complications in women with prior cold-knife conization. METHODS: In a retrospective study, we compared 76 deliveries of 65 women with prior cold-knife conization with the remaining 29,711 singleton deliveries at our institution between 1992 and 2002. RESULTS: We found significant shorter duration of pregnancies in the conization group. Delivery prior to 37 weeks was found in 22.4% (n = 17) of the conization group and in 6.6% (n = 1961) of the controls (OR = 4.07 [2.22-7.10], P < 0.001). Preterm premature rupture of the membranes was found in 17.1% (n = 13) of the conization group and in 2.6% (n = 775) of the controls (OR = 7.70 [3.87-14.21], P < 0.001). Birth weight less than 2500 g was found in 18.4% (n = 14) of the conization group and in 7.7% (n = 2280) of the controls (OR = 2.72 [1.40-4.92], P = 0.002). Overall, birth weight in the conization group was not significantly lower (median 3147 g vs. 3287 g, P = 0.115). Cervical tears were found more frequently in the conization group (8.8% [n = 6] vs. 1.3% [n = 236], OR = 7.53 [2.63-17.57], P < 0.001). There was no difference in mode of delivery, duration of labor, head circumference, chorioamnionitis and use of oxytocin. CONCLUSION: Cold-knife conization is a risk factor for preterm birth and preterm premature rupture of the membranes and seems to be a risk factor for cervical tears.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Birth Weight -
- Cervical Intraepithelial Neoplasia - surgery
- Conization - adverse effects
- Cryosurgery - adverse effects
- Female - adverse effects
- Humans - adverse effects
- Middle Aged - adverse effects
- Pregnancy - adverse effects
- Pregnancy Outcome - adverse effects
- Premature Birth - etiology
- Retrospective Studies - etiology
- Uterine Cervical Neoplasms - surgery
- Find related publications in this database (Keywords)
- conization
- pregnancy
- preterm delivery
- pPROM
- cervical intraepithelial neoplasia