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Pavlović, M; Matko, Š; Prüfer, F; Löfler, S; Fischer, MJ; Grote, V; Šarabon, N.
Health-Related Quality of Life, Body Mass Index and the 10-Metre Walk Test in Patients Awaiting Total Knee or Hip Arthroplasty: A Cross-Sectional Data Analysis with Matched Controls.
Life (Basel). 2025; 15(2): Doi: 10.3390/life15020231 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

Leading authors Med Uni Graz: Grote Vincent Thomas
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Abstract:: The study compares the body mass index (BMI), 10-m walk test results, and self-rated health-related quality of life (HRQoL) of patients awaiting total knee or hip arthroplasty with age and sex-matched controls. Additionally, we investigated relationships between these variables to better understand how mobility impairments and HRQoL contribute to the need for surgical intervention. Forty-three patients (age: 66.7 ± 8.7 years) awaiting total knee arthroplasty (n = 23) or total hip arthroplasty (n = 20) and 54 healthy control individuals (age: 65.6 ± 1.5 years) participated in this study. Weight and height were measured, the BMI was calculated, the 10 m walk test was performed, and HRQoL was assessed using the EQ-5D-5L questionnaire. Patients had a significantly higher BMI than controls (p = 0.037), with the majority of both groups classified as overweight or obese (patients, 86%; controls, 73%). Patients also walked significantly more slowly than controls (p < 0.001). HRQoL was significantly lower in patients across all dimensions (p < 0.001), with the greatest impairments observed in mobility, usual activities, and pain. Significant but weak correlations (p = 0.001-0.042, r_s = 0.31-0.48) were found between the HRQoL, BMI, and 10 m walk test results. These findings confirm that patients awaiting total knee or hip arthroplasty exhibit an increased BMI, reduced locomotor function, and impaired HRQoL, highlighting the extent of functional limitations in individuals with end-stage osteoarthritis. The strong association between mobility impairments and HRQoL further underscores the impact of osteoarthritis on daily life and the increasing need for surgical intervention.
Find related publications in this database (Keywords): osteoarthritis; arthroplasty; knee replacement; hip replacement; health-related quality of life; body mass index; walking speed