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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Coti, I; Haberl, T; Scherzer, S; Werner, P; Shabanian, S; Kocher, A; Laufer, G; Andreas, M.
Outcome of rapid deployment aortic valves: long-term experience after 700 implants
ANN CARDIOTHORAC SUR. 2020; 9(4): 314-321.
Doi: 10.21037/acs.2020.04.01
Web of Science
PubMed
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- Co-authors Med Uni Graz
- Andreas Martin
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- Abstract:
- Background: The Edwards Intuity Valve System is a bioprosthesis with a balloon-expandable stent frame which enables rapid-deployment (RD). We aimed to analyze our single-center long-term experience with a follow-up until 9 years after aortic valve replacement (AVR) with this bioprosthesis. Methods: Between May 2010 and May 2019, 700 consecutive patients with severe aortic stenosis or combined aortic valve disease, implanted with a RD valve at our institution, were included in a prospective database. Median follow-up was 19 months and the total accumulated follow-up was 2,140 patient-years. Pre-operative characteristics, operative parameters, survival rates, valve-related adverse events and valve hemodynamics were assessed. Results: Mean age was 74 +/- 8 years, 45% female. Concomitant procedures were performed in 339 (48.4%) patients. In case of isolated AVR (361/700), a minimally invasive surgical (MIS) approach was conducted in 283 patients (78.4%). Cardio-pulmonary bypass (CPB) and cross-clamp times for isolated AVR were 107.7 +/- 28.2 and 73.8 +/- 21.3 minutes for MIS approaches and 92.8 +/- 28.8 and 57.5 +/- 20.6 minutes for full stemotomy (P4.001), respectively. Mean gradients at discharge, 1, 3 and 5 years were 13 +/- 5, 11 +/- 4, 12 +/- 5 and 13 +/- 8 mmHg. New early pacemaker implantation was required in 8.9% of patients. Re-intervention or reoperation with valve explantation for structural degeneration, non-structural dysfunction or endocarditis, occurred in 21 cases (3%). Thirty-day mortality was 0.7% (5/700) and overall survival at 1, 3 and 5 years was 98%, 91% and 76%. Conclusions: We report excellent long-term results in this updated single center experience for RD aortic valves regarding durability, safety and hemodynamic performance.
- Find related publications in this database (Keywords)
- Aortic valve replacement (AVR)
- rapid-deployment (RD)
- valve hemodynamic
- valve explantation