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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Di Eusanio, M; Phan, K; Berretta, P; Carrel, TP; Andreas, M; Santarpino, G; Di Bartolomeo, R; Folliguet, T; Meuris, B; Mignosa, C; Martinelli, G; Misfeld, M; Glauber, M; Kappert, U; Shrestha, M; Albertini, A; Teoh, K; Villa, E; Yan, T; Solinas, M.
Sutureless and Rapid-Deployment Aortic Valve Replacement International Registry (SURD-IR): early results from 3343 patients
EUR J CARDIO-THORAC. 2018; 54(4): 768-773.
Doi: 10.1093/ejcts/ezy132
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- Co-authors Med Uni Graz
- Andreas Martin
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- Abstract:
- OBJECTIVES: The Sutureless and Rapid-Deployment Aortic Valve Replacement International Registry (SURD-IR) was established by a consortium of 18 research centres-the International Valvular Surgery Study Group (IVSSG)-to overcome limitations of the literature and provide adequately powered evidence on sutureless and rapid-deployment aortic valves replacement (SURD-AVR). METHODS: Data from 3343 patients undergoing SURD-AVR over a 10-year period (2007-2017) were collected in the registry. The mean age of the patients was 76.8 +/- 6.7 years, with 36.4% being 80 years or older. The average logistic EuroSCORE was 11.3 +/- 9.7%. RESULTS: Isolated SURD-AVR was performed in 70.7% (n = 2362) of patients using full sternotomy (35.3%) or less invasive approaches (64.8%). Overall hospital mortality was 2.1%, being 1.4% in patients who had isolated SURD-AVR and 3.5% in those who had concomitant procedures (P < 0.001). When considering baseline risk profile, mortality rate was 0.8% and 1.9% in low risk (logistic EuroSCORE < 10%) isolated SURD-AVR and combined SURD-AVR, respectively, and 2.2% and 3.7% in higher risk patients (logistic EuroSCORE > 10%). Postoperative neurological complications included stroke (2.8%) and transient ischaemic attack (1.1%). New atrioventricular block requiring pacemaker occurred in 10.4% of the patients. The rate of pacemaker implantation significantly decreased over time [from 17.2% (2007-2008) to 5.4% (2016); P = 0.02]. CONCLUSIONS: Our findings showed that SURD-AVR is a safe and effective alternative to conventional aortic valve replacement and is associated with excellent clinical outcomes. Further adequately powered statistical analyses from the retrospective and prospective SURDIR will allow for the development of high-quality evidence-based clinical guidelines for SURD-AVR.
- Find related publications in this database (Keywords)
- Sutureless valve
- Rapid-deployment valve
- Aortic valve replacement
- Sutureless and Rapid-Deployment Aortic Valve Replacement International Registry
- The International Valvular Surgery Study Group