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Baik-Schneditz, N; Pfurtscheller, D; Wolfsberger, CH; Schwaberger, B; Höller, N; Urlesberger, B; Avian, A; Pichler, G.
Reference Ranges for Cerebral Oxygenation in Neonates During Immediate Transition After Birth: Differences Between Devices.
Acta Paediatr. 2025; 114(6):1379-1384 Doi: 10.1111/apa.17580 [OPEN ACCESS]
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Leading authors Med Uni Graz: Baik-Schneditz Nariae; Pichler Gerhard
Co-authors Med Uni Graz: Avian Alexander; Höller Nina; Pfurtscheller Daniel; Schwaberger Bernhard; Urlesberger Berndt; Wolfsberger Christina Helene
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Abstract:: AIM: The aim was to define reference ranges for cerebral oxygen saturation (crSO₂-ROOT) during immediate transition after birth in stable neonates. METHODS: In a prospective observational study, the crSO₂-ROOT was continuously measured in neonates during the first 15 min after birth. The neonatal sensor was placed on the head and fixed with a bandage. Median values and 10th and 90th centiles were calculated for each minute. Additionally, cerebral fractional tissue oxygen extraction (cFTOE-ROOT) was calculated using crSO₂-ROOT and arterial oxygen saturation (SpO₂) measured with pulse oximetry. These crSO-ROOT values were compared with already published reference ranges of cerebral oxygen saturation measured using different devices: crSO₂-INVOS and cTOI-NIRO. RESULTS: The data of 122 neonates (14 preterm/108 term neonates) were analysed. The crSO₂-ROOT values had a similar course when compared to cTOI-NIRO values, whereas crSO₂-INVOS values were initially lower and exceeded during the first minutes after birth. CONCLUSION: The present observational study added reference ranges of crSO₂-ROOT in stable neonates immediately after birth. As there are differences regarding reference ranges of various near-infrared spectroscopy (NIRS) devices, it is important to be aware of this information for future clinical use.
Find related publications in this database (using NLM MeSH Indexing): Humans - administration & dosage; Infant, Newborn - administration & dosage; Prospective Studies - administration & dosage; Reference Values - administration & dosage; Female - administration & dosage; Male - administration & dosage; Oxygen Saturation - administration & dosage; Spectroscopy, Near-Infrared - instrumentation; Oximetry - instrumentation; Oxygen - blood; Brain - metabolism
Find related publications in this database (Keywords): brain monitoring; cerebral oxygen saturation; near-infrared spectroscopy; neonatal transition; reference range