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SHR Neuro Cancer Cardio Lipid Metab Microb

Atanasov, G; Schmelzle, M; Thelen, A; Wiltberger, G; Hau, HM; Krenzien, F; Petersen, TO; Moche, M; Jonas, S.
Selective hypertrophy of the lobus caudatus as a novel approach enabling extended right hepatectomy in the presence of a non-perfused left lateral liver lobe.
Clin J Gastroenterol. 2014; 7(4): 370-5. Doi: 10.1007/s12328-014-0511-5 (- Case Report) [OPEN ACCESS]
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Co-authors Med Uni Graz: Hau Hans-Michael
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Abstract:: INTRODUCTION: Portal vein embolization (PVE) is a well-established technique to enhance functional hepatic reserves of segments II and III before curative extended right hepatectomy for tumors of the right liver lobe. However, an adequate hepatopetal flow of the left lateral portal vein branches is required for a sufficient PVE-associated hypertrophy. CASE REPORT: Here, we report a 65-year old patient suffering from a locally advanced intrahepatic cholangiocarcinoma in the right liver lobe and segment IV. A curative extended right hepatectomy after preoperative PVE of liver segments IV-VIII was initially impossible because of partial thrombosis of the left lateral portal vein branches resulting in an ischemic-type atrophy of segments II and III. However, due to a massive hypertrophy of the caudate lobe following PVE of liver segments IV-VIII, subsequent extended right hepatectomy with intraoperative thrombectomy of segments II and III was made possible. CONCLUSIONS: To our knowledge this is the first case in which an extended right hepatectomy for a liver malignancy, in the presence of atrophic left lateral section, was made possible by a massive PVE-associated hypertrophy of the caudate lobe.
Find related publications in this database (using NLM MeSH Indexing): Aged - administration & dosage; Cholangiocarcinoma - therapy; Embolization, Therapeutic - administration & dosage; Female - administration & dosage; Hepatectomy - methods; Humans - administration & dosage; Hypertrophy - administration & dosage; Liver - blood supply, pathology; Liver Neoplasms - therapy; Portal Vein - administration & dosage