Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Benzing, C; Krezdorn, N; Förster, J; Hinz, A; Krenzien, F; Atanasov, G; Schmelzle, M; Hau, HM; Bartels, M.
Health-related quality of life and affective status in liver transplant recipients and patients on the waiting list with low MELD scores.
HPB (Oxford). 2016; 18(5): 449-55.
Doi: 10.1016/j.hpb.2016.01.546
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- Co-Autor*innen der Med Uni Graz
- Hau Hans-Michael
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- Abstract:
- BACKGROUND: This study seeks to examine the impact of orthotopic liver transplantation (OLT) on Health-Related Quality of Life (HRQoL) and mental health in patients with different MELD scores. METHODS: Patients who has undergone orthotopic liver transplant (OLT) or were on the waiting list for OLT were submitted to HRQoL and depression/anxiety assessment by questionnaire: Short-Form 36 (SF-36), Questions on Life Satisfaction (FLZ-M), Patient Health Questionnaire-4 (PHQ-4). Data were analysed following division of patients into three groups: pretransplant patients with a MELD score <10, ≥10, and OLT recipients. RESULTS: The surveys were sent to 940 consecutive patients within one week in June 2013. Of these 940 patients, 869 (92.4%) met the inclusion criteria. In total, 291 (33.5%) eligible questionnaires (OLT group: 235, MELD <10: 25; MELD _10: 31) were suitable for analysis. General health (GH), vitality (VIT), and mental health (MH) were lower in both pretransplant groups compared to the OLT group (all p < 0.05). Anxiety and depression were higher in the MELD <10 group than in the OLT group (anxiety: p < 0.05; depression: p < 0.01). DISCUSSION: Patients with low MELD scores seem to benefit from OLT with regards to HRQoL and mental health.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent - administration & dosage
- Adult - administration & dosage
- Aged - administration & dosage
- Anxiety - psychology
- Cross-Sectional Studies - administration & dosage
- Depression - psychology
- End Stage Liver Disease - diagnosis, physiopathology, psychology, surgery
- Female - administration & dosage
- Health Status - administration & dosage
- Humans - administration & dosage
- Liver Transplantation - administration & dosage
- Male - administration & dosage
- Mental Health - administration & dosage
- Middle Aged - administration & dosage
- Personal Satisfaction - administration & dosage
- Quality of Life - administration & dosage
- Retrospective Studies - administration & dosage
- Surveys and Questionnaires - administration & dosage
- Transplant Recipients - psychology
- Treatment Outcome - administration & dosage
- Waiting Lists - administration & dosage
- Young Adult - administration & dosage