Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Morgul, MH; Splith, K; Leonhardt, C; Raschzok, N; Reutzel-Selke, A; Schmuck, RB; Andreou, A; Atanasov, G; Benzing, C; Krenzien, F; Hau, HM; Felgendreff, P; Klunk, S; Pratschke, J; Sauer, IM; Schmelzle, M.
The value of microparticles in detecting acute rejection episodes after liver transplantation.
Biomarkers. 2018; 23(1): 25-32.
Doi: 10.1080/1354750X.2017.1306754
Web of Science
PubMed
FullText
FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Hau Hans-Michael
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- Abstract:
- CONTEXT: Non-invasive markers for diagnosis of acute rejection (AR) following liver transplantation have not been developed, yet. OBJECTIVE: We analyzed the correlation of plasma microparticle levels (MP) with AR. MATERIALS AND METHODS: MP (CD4, CD8, CD25, CD31, MHC) of 11 AR patients and 11 controls were analyzed within the first week after transplantation. RESULTS: CD4, CD8 and CD31 positive MP were higher in the AR, whereas overall MP count, CD25 and MHCI positive MP proportions did not differ between both groups. DISCUSSION AND CONCLUSION: MP dynamics within the first period of transplantation could help to clarify on-going mechanisms of immunomodulation.
- Find related publications in this database (using NLM MeSH Indexing)
- CD4 Antigens - blood
- CD8 Antigens - blood
- Cell-Derived Microparticles - metabolism
- Female - administration & dosage
- Graft Rejection - blood, diagnosis, etiology
- Humans - administration & dosage
- Liver Transplantation - adverse effects, methods
- Male - administration & dosage
- Middle Aged - administration & dosage
- Platelet Endothelial Cell Adhesion Molecule-1 - blood
- Time Factors - administration & dosage
- Find related publications in this database (Keywords)
- T cell-derived microparticles
- endothelial cell-derived microparticles
- regulatory T cells
- graft monitoring
- non-invasive marker