Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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SHR Neuro Krebs Kardio Lipid Stoffw Microb

Hau, HM; Tautenhahn, HM; Schmelzle, M; Krenzien, F; Schoenberg, MB; Morgul, MH; Uhlmann, D; Wiltberger, G; Rasche, M; Bachmann, A; Jonas, S; Bartels, M.
Management of urologic complications in renal transplantation: a single-center experience.
Transplant Proc. 2014; 46(5): 1332-9. Doi: 10.1016/j.transproceed.2014.04.002
Web of Science PubMed FullText FullText_MUG

Führende Autor*innen der Med Uni Graz: Hau Hans-Michael
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Abstract:: INTRODUCTION: Ureterovesical complications subsequent to renal transplantation are associated with a high morbidity leading to graft loss or even death. In the present study, the management of these complications by using interventional and surgical procedures (native pyeloureterostomy [NPUS]/ureteroureterostomy [NUU] vs ureteroneocystostomy [UNC]) was evaluated retrospectively. PATIENTS AND METHODS: Between 1994 and 2012, a total of 780 kidney transplantations (690 deceased and 90 living donors) were performed at our institution. Demographic, clinical, and laboratory data from patients with urologic complications were analyzed and compared. RESULTS: Fifty patients (6.4%) exhibited ureterovesical complications, and 18 patients (36%) were operated on immediately. In 32 (64%) of 50 patients, an interventional procedure was initially performed, with 21 patients (66%) undergoing operation due to therapy failure. NPUS/NUU and UNC were performed in 26 (66.6%) and 13 (33.3%) patients, respectively. Indications for an operation were ureteral stenosis in 12 patients (30.8%), ureteral necrosis and urine leakage in 19 patients (48.7%), and symptomatic vesicoureteral reflux in 8 patients (20.5%). Long-term results were comparable between all groups. CONCLUSIONS: Surgical revision of ureteral complications should be the standard therapy. NPUS/NUU, UNC, and the successful interventional procedures did not differ significantly in terms of long-term results.
Find related publications in this database (using NLM MeSH Indexing): Female - administration & dosage; Germany - administration & dosage; Humans - administration & dosage; Kidney Transplantation - adverse effects; Male - administration & dosage; Middle Aged - administration & dosage; Urologic Diseases - etiology, therapy