Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Broschewitz, J; Wiltberger, G; Krezdorn, N; Krenzien, F; Förster, J; Atanasov, G; Hau, HM; Schmelzle, M; Hinz, A; Bartels, M; Benzing, C.
Primary liver transplantation and liver retransplantation: comparison of health-related quality of life and mental status - a cross-sectional study.
Health Qual Life Outcomes. 2017; 15(1): 147
Doi: 10.1186/s12955-017-0723-8
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- Co-Autor*innen der Med Uni Graz
- Hau Hans-Michael
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- Abstract:
- BACKGROUND: Liver Retransplantation (Re-LT) procedures are associated with an increased risk of morbidity and mortality. Up to date, there is no knowledge on the health-related quality of life and the mental status of these patients. METHODS: Health-Related Quality of Life (HRQoL) was assessed by using the Short Form 36 (SF-36) Health Survey and Mental Status was assessed by using the Hospital Anxiety and Depression Scale (HADS). The patients were examined in different assessments: During regular check-up examinations in the LT outpatient department in 2011 (Survey 1) and in a postal survey in 2013 (Survey 2). Their medical data was collected by using an established database. RESULTS: We received eligible surveys of 383 patients (55.6%) with a history of LT, of which 15 (3.9%) had undergone Re-LT (Re-LT group). These patients were compared to a group of 60 patients who had undergone only one LT. With regard to their HRQoL, the Re-LT group had significantly lower scores on the scales of physical function (PF, p = 0.026), their role-physical (RP, p = 0.008), their vitality (VIT, p = 0.040), and their role-emotional (RE, p = 0.005). The scores for anxiety and depression did not differ significantly between the groups. In a multiple regression analysis, chronic kidney disease was found to be an independent risk factor for decreased scores of PF (p = 0.023). CONCLUSIONS: Patients who have to undergo Re-LT procedures are faceing impairments in physical aspects of a HRQoL. Together with clinical results from other studies, the findings of the present examination underline the need for an optimized organ distribution strategy since not all patients listed for Re-LT appear to benefit from it.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult - administration & dosage
- Anxiety - psychology
- Cross-Sectional Studies - administration & dosage
- Depression - psychology
- Female - administration & dosage
- Humans - administration & dosage
- Liver Transplantation - psychology
- Male - administration & dosage
- Middle Aged - administration & dosage
- Quality of Life - administration & dosage
- Reoperation - psychology
- Risk Factors - administration & dosage
- Surveys and Questionnaires - administration & dosage
- Find related publications in this database (Keywords)
- Health-related quality of life
- Liver retransplantation
- SF-36
- Hads
- Depression
- Anxiety