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Peikert, A; Solomon, SD.
Contemporary treatment options in heart failure with preserved ejection fraction.
Eur Heart J Cardiovasc Imaging. 2024; 25(11):1517-1524 Doi: 10.1093/ehjci/jeae201
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Leading authors Med Uni Graz
Peikert Alexander
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Abstract:
Heart failure with preserved ejection fraction (HFpEF) constitutes approximately half of the heart failure population, with its prevalence markedly increasing with older age and the presence of cardio-metabolic comorbidities. Although HFpEF is associated with a high symptom- and mortality burden, historically there have been few evidence-based treatment options for patients with HFpEF. Recent randomized clinical trials have expanded evidence on pharmacological treatment options, introducing new agents for managing HFpEF. Given the complex clinical phenotype with pathophysiological heterogeneity and evolving diagnostic standards, the evidence-based management of HFpEF remains challenging for clinicians. This review summarizes the latest evidence from contemporary randomized clinical trials and recent guideline recommendations to provide guidance for the treatment of patients with HFpEF.
Find related publications in this database (using NLM MeSH Indexing)
Humans - administration & dosage
Heart Failure - therapy, physiopathology
Stroke Volume - physiology
Aged - administration & dosage
Female - administration & dosage
Male - administration & dosage
Randomized Controlled Trials as Topic - administration & dosage
Practice Guidelines as Topic - administration & dosage
Risk Assessment - administration & dosage
Prognosis - administration & dosage

Find related publications in this database (Keywords)
heart failure with preserved ejection fraction
guideline-directed medical therapeutics
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