Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Unterlechner, D; Amrein, K.
Vitamin D and prediabetes
J ENDOKRINOL DIAB ST. 2024;
Doi: 10.1007/s41969-024-00245-3
Web of Science
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- Führende Autor*innen der Med Uni Graz
- Amrein Karin
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- Abstract:
- In a recent analysis of three randomized controlled trials, a significant benefit of vitamin D administration was found for people with prediabetes on the risk of developing type 2 diabetes mellitus. With a number needed to treat (NNT) of 30, vitamin D is not far behind other interventions such as profound lifestyle change (NNT = 7) or metformin (NNT = 14). In absolute terms, vitamin D supplementation achieved a risk reduction of 3.3%. In particular, patients with a body mass index (BMI) below 30 kg/m(2) and a low baseline vitamin D level seemed to benefit in particular. This is also emphasized by the Endocrine Society in its new clinical guidelines on vitamin D supplementation which are recommended for a wide range of people. In view of the increasing rates of insulin resistance/type 2 diabetes mellitus and the high prevalence of vitamin D deficiency, it is important to use this simple and inexpensive option.
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