Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Kimmerle, AR; Noflatscher, M; Raggam, RB.
Optimal long-term anticoagulation after acute pulmonary embolism: current state of the art and a look into the near future.
Curr Opin Pulm Med. 2024; 30(5):421-428
Doi: 10.1097/MCP.0000000000001106
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Kimmerle Andreas Rainer
- Raggam Reinhard Bernd
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- Abstract:
- PURPOSE OF REVIEW: This review aims to summarize the current state of the art and future directions in optimal long-term anticoagulation following acute pulmonary embolism (PE). RECENT FINDINGS: Actual studies and guidelines underscore the preference for direct oral anticoagulants (DOAC) in standard therapeutic doses for maintenance therapy post-PE, while considering patient-specific factors and dose-reduction criteria. Risk stratification should always include the assessment of concomitant trigger- or risk factors regarding their strength and persistence. The use of tools like specific scores can facilitate the identification of optimal candidates for long-term therapy, emphasizing once more personalized approaches and strategies. Special patient groups, such as cancer associated thrombosis, chronic thromboembolic pulmonary hypertension or antiphospholipid syndrome require even more tailored therapy approaches. SUMMARY: Optimal long-term anticoagulation post-PE should be guided by straightforward and individual risk assessment strategies. The array of indications for DOACs has gotten wider in last years, also within special patient groups. Still, chronic thromboembolic pulmonary hypertension and antiphospholipid syndrome remains domain of vitamin K agonists.
- Find related publications in this database (using NLM MeSH Indexing)
- Humans - administration & dosage
- Pulmonary Embolism - drug therapy
- Anticoagulants - administration & dosage, therapeutic use
- Risk Assessment - administration & dosage
- Acute Disease - administration & dosage
- Risk Factors - administration & dosage
- Administration, Oral - administration & dosage
- Practice Guidelines as Topic - administration & dosage
- Find related publications in this database (Keywords)
- long-term anticoagulation
- pulmonary embolism
- recurrence of venous thromboembolism
- risk stratification