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SHR Neuro Cancer Cardio Lipid Metab Microb
Halimi, JM; Sarafidis, P; Azizi, M; Bilo, G; Burkard, T; Bursztyn, M; Camafort, M; Chapman, N; Cottone, S; de, Backer, T; Deinum, J; Delmotte, P; Dorobantu, M; Doumas, M; Dusing, R; Duly-Bouhanick, B; Fauvel, JP; Fesler, P; Gaciong, Z; Gkaliagkousi, E; Gordin, D; Grassi, G; Grassos, C; Guerrot, D; Huart, J; Izzo, R; Jaén, Águila, F; Járai, Z; Kahan, T; Kantola, I; Kociánová, E; Limbourg, F; Lopez-Sublet, M; Mallamaci, F; Manolis, A; Marketou, M; Mayer, G; Mazza, A; MacIntyre, I; Mourad, JJ; Muiesan, ML; Nasr, E; Nilsson, P; Oliveras, A; Ormezzano, O; Paixão-Dias, V; Papadakis, I; Papadopoulos, D; Perl, S; Polónia, J; Pontremoli, R; Pucci, G; Robles, NR; Rubin, S; Ruilope, LM; Rump, LC; Saeed, S; Sanidas, E; Sarzani, R; Schmieder, R; Silhol, F; Sokolovic, S; Solbu, M; Soucek, M; Stergiou, G; Sudano, I; Tabbalat, R; Tengiz, I; Triantafyllidi, H; Tsioufis, K; Václavík, J; van, der, Giet, M; der, Niepen, PV; Veglio, F; Venzin, R; Viigimaa, M; Weber, T; Widimsky, J; Wuerzner, G; Zelveian, P; Zebekakis, P; Lueders, S; Persu, A; Kreutz, R; Vogt, L.
Management of patients with hypertension and chronic kidney disease referred to Hypertension Excellence Centres among 27 countries. On behalf of the European Society of Hypertension Working Group on Hypertension and the Kidney.
Blood Press. 2024; 33(1):2368800
Doi: 10.1080/08037051.2024.2368800
Web of Science
PubMed
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- Co-authors Med Uni Graz
- Perl Sabine
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- Abstract:
- Objective Real-life management of patients with hypertension and chronic kidney disease (CKD) among European Society of Hypertension Excellence Centres (ESH-ECs) is unclear : we aimed to investigate it. Methods A survey was conducted in 2023. The questionnaire contained 64 questions asking ESH-ECs representatives to estimate how patients with CKD are managed. Results Overall, 88 ESH-ECS representatives from 27 countries participated. According to the responders, renin-angiotensin system (RAS) blockers, calcium-channel blockers and thiazides were often added when these medications were lacking in CKD patients, but physicians were more prone to initiate RAS blockers (90% [interquartile range: 70-95%]) than MRA (20% [10-30%]), SGLT2i (30% [20-50%]) or (GLP1-RA (10% [5-15%]). Despite treatment optimisation, 30% of responders indicated that hypertension remained uncontrolled (30% (15-40%) vs 18% [10%-25%]) in CKD and CKD patients, respectively). Hyperkalemia was the most frequent barrier to initiate RAS blockers, and dosage reduction was considered in 45% of responders when kalaemia was 5.5-5.9 mmol/L. Conclusions RAS blockers are initiated in most ESH-ECS in CKD patients, but MRA and SGLT2i initiations are less frequent. Hyperkalemia was the main barrier for initiation or adequate dosing of RAS blockade, and RAS blockers' dosage reduction was the usual management.
- Find related publications in this database (using NLM MeSH Indexing)
- Humans - administration & dosage
- Renal Insufficiency, Chronic - complications, drug therapy
- Hypertension - drug therapy
- Europe - administration & dosage
- Antihypertensive Agents - therapeutic use
- Male - administration & dosage
- Surveys and Questionnaires - administration & dosage
- Female - administration & dosage
- Middle Aged - administration & dosage
- Calcium Channel Blockers - therapeutic use
- Societies, Medical - administration & dosage
- Angiotensin Receptor Antagonists - therapeutic use
- Find related publications in this database (Keywords)
- Chronic kidney disease
- hypertension
- management
- RAS blockers
- hyperkalaemia
- SGLT2 inhibitors
- mineralocorticoid receptor antagonists
- guidelines