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Mujanovic, A; Ng, FC; Branca, M; Deutschmann, HA; Meinel, TR; Churilov, L; Nistl, O; Mitchell, PJ; Yassi, N; Parsons, MW; Sharma, GJ; Gattringer, T; Arnold, M; Cavalcante, F; Piechowiak, EI; Kleinig, TJ; Seiffge, DJ; Dobrocky, T; Gralla, J; Fischer, U; Kneihsl, M; Campbell, BCV; Kaesmacher, J.
External Validation of a Model for Persistent Perfusion Deficit in Patients With Incomplete Reperfusion After Thrombectomy: EXTEND-PROCEED.
Neurology. 2024; 103(2): e209401
Doi: 10.1212/WNL.0000000000209401
[OPEN ACCESS]
Web of Science
PubMed
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- Co-authors Med Uni Graz
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Deutschmann Hannes
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Gattringer Thomas
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Kneihsl Markus
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Nistl Oliver
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- Abstract:
- BACKGROUND AND OBJECTIVES: We recently developed a model (PROCEED) that predicts the occurrence of persistent perfusion deficit (PPD) at 24 hours in patients with incomplete angiographic reperfusion after thrombectomy. This study aims to externally validate the PROCEED model using prospectively acquired multicenter data. METHODS: Individual patient data for external validation were obtained from the Endovascular Therapy for Ischemic Stroke with Perfusion-Imaging Selection, Tenecteplase versus Alteplase Before Endovascular Therapy for Ischemic Stroke part 1 and 2 trials, and a prospective cohort of the Medical University of Graz. The model's primary outcome was the occurrence of PPD, defined as a focal, wedge-shaped perfusion delay on 24-hour follow-up perfusion imaging that corresponds to the capillary phase deficit on last angiographic series in patients with
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Thrombectomy - methods
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Middle Aged - administration & dosage
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