Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Kahraman, G; Krepler, K; Franz, C; Ries, E; Maar, N; Wedrich, A; Rieger, A; Dejaco-Ruhswurm, I.
Seven years of HAART impact on ophthalmic management of HIV-infected patients.
OCUL IMMUNOL INFLAMM. 2005; 13: 213-218.
Doi: 10.1080/09273940490912443
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Wedrich Andreas
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- Abstract:
- PURPOSE: The widespread use of highly active antiretroviral therapy (HAART) has changed the clinical picture of HIV-associated eye disease. We evaluated the incidence of ocular manifestations of HIV infection since the introduction of HAART. METHODS: Between January 1996 and December 2002, we examined 539 HIV-infected patients in our hospital. Follow-up of the patients was performed in case of ophthalmologic symptoms, regardless of current immunologic status, or for screening. RESULTS: A total of 217 patients (40.3%) had HIV-associated eye disease. Of these patients, 42.0% had no eye symptoms. Fifty-eight (10.8%) of the 539 patients had cytomegalovirus (CMV) retinitis, most of whom had CMV retinitis before receiving HAART. Four patients developed immune-recovery uveitis. A total of 145 patients (26.9%) had HIV-related microangiopathy and 96 (17.8%) had dry-eye syndrome. CONCLUSION: The introduction of HAART had a major impact on the medical history of patients with HIV-related eye disease with improved survival time and decreased morbidity.
- Find related publications in this database (using NLM MeSH Indexing)
- AIDS-Related Opportunistic Infections - drug therapy
- Adolescent - drug therapy
- Adult - drug therapy
- Aged - drug therapy
- Anti-HIV Agents - therapeutic use
- Antiretroviral Therapy, Highly Active - therapeutic use
- Austria - epidemiology
- CD4 Lymphocyte Count - epidemiology
- Comparative Study - epidemiology
- Cytomegalovirus Retinitis - drug therapy
- Female - drug therapy
- Follow-Up Studies - drug therapy
- HIV-1 - genetics
- Humans - genetics
- Incidence - genetics
- Male - genetics
- Middle Aged - genetics
- RNA, Viral - genetics
- Retrospective Studies - genetics
- Treatment Outcome - genetics
- Find related publications in this database (Keywords)
- acquired immunodeficiency syndrome ( AIDS)
- cytomegalovirus (CMV) retinitis
- highly active antiretroviral therapy (HAART)
- HIV infection