Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
de, Man, AME; Amrein, K; Casaer, MP; Dizdar, OS; van, Zanten, ARH; Gundogan, K; Lepp, L; Rezzi, S; Shenkin, A; Berger, MM, , ESPEN, MN, special, interest, group.
LLL 44-4 : Micronutrients in acute disease and critical illness.
Clin Nutr ESPEN. 2024; 61:437-446
Doi: 10.1016/j.clnesp.2024.04.011
Web of Science
PubMed
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FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Amrein Karin
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- Abstract:
- Micronutrients (MN), i.e. trace elements and vitamins, are essential components of the diet in relatively small amounts in any form of nutrition, with special needs in critically ill patients. Critical illness is characterised by the presence of inflammation and oxidative stress. MNs are tightly involved in antioxidant and immune defences. In addition, some conditions, and treatments result in large losses of biological fluids containing MNs: therefore, acute renal injury requiring renal replacement therapy, acute intestinal failure, and major burns and trauma are at high risk of acute depletion of body stores, and of deficiency. MN requirements are increased above standard DRI. Blood level interpretation is complicated by inflammation: some biomarkers assist the status determination. Due to the acute challenges of critical illness, it of utmost importance to cover the needs to maintain the organism's endogenous immune and antioxidant defences, and capacity to repair tissues. Practical strategies are proposed.
- Find related publications in this database (using NLM MeSH Indexing)
- Humans - administration & dosage
- Micronutrients - blood
- Critical Illness - administration & dosage
- Oxidative Stress - administration & dosage
- Antioxidants - metabolism
- Acute Disease - administration & dosage
- Nutritional Requirements - administration & dosage
- Trace Elements - blood
- Inflammation - administration & dosage
- Nutritional Status - administration & dosage
- Vitamins - blood
- Biomarkers - blood
- Find related publications in this database (Keywords)
- Refeeding syndrome
- Intestinal failure
- In flammation
- Immunity
- Sepsis
- Acute kidney injury
- Heart failure