Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Freinhofer, D; Schwartenbeck, P; Thon, N; Aichhorn, W; Lenger, M; Wurst, FM; Kronbichler, M.
Loss, gain and choice difficulty in gambling patients: Neural and behavioural processes.
Addict Biol. 2024; 29(5):e13396
Doi: 10.1111/adb.13396
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Lenger Melanie
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Impaired decision-making is often displayed by individuals suffering from gambling disorder (GD). Since there are a variety of different phenomena influencing decision-making, we focused in this study on the effects of GD on neural and behavioural processes related to loss aversion and choice difficulty. Behavioural responses as well as brain images of 23 patients with GD and 20 controls were recorded while they completed a mixed gambles task, where they had to decide to either accept or reject gambles with different amounts of potential gain and loss. We found no behavioural loss aversion in either group and no group differences regarding loss and gain-related choice behaviour, but there was a weaker relation between choice difficulty and decision time in patients with GD. Similarly, we observed no group differences in processing of losses or gains, but choice difficulty was weaker associated with brain activity in the right anterior insula and anterior cingulate cortex in patients with GD. Our results showed for the first time the effects of GD on neural processes related to choice difficulty. In addition, our findings on choice difficulty give new insights on the psychopathology of GD and on neural processes related to impaired decision-making in GD.
- Find related publications in this database (using NLM MeSH Indexing)
- Humans - administration & dosage
- Gambling - physiopathology, diagnostic imaging, psychology
- Male - administration & dosage
- Adult - administration & dosage
- Choice Behavior - physiology
- Magnetic Resonance Imaging - administration & dosage
- Female - administration & dosage
- Gyrus Cinguli - diagnostic imaging, physiopathology
- Decision Making - physiology
- Case-Control Studies - administration & dosage
- Middle Aged - administration & dosage
- Brain - diagnostic imaging, physiopathology
- Brain Mapping - methods
- Insular Cortex - diagnostic imaging
- Young Adult - administration & dosage
- Find related publications in this database (Keywords)
- choice difficulty
- decision-making
- fMRI
- gambling
- loss aversion