Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Pfurtscheller, D; Schwaberger, B; Höller, N; Baik-Schneditz, N; Schober, L; Bruckner, M; Schlatzer, C; Urlesberger, B; Pichler, G.
Cardiac output calculation using the Liljestrand and Zander formula: is this method applicable during immediate transition after birth? - A post hoc analysis.
Eur J Pediatr. 2024; 183(8):3617-3622
Doi: 10.1007/s00431-024-05592-6
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- Führende Autor*innen der Med Uni Graz
- Pfurtscheller Daniel
- Pichler Gerhard
- Co-Autor*innen der Med Uni Graz
- Baik-Schneditz Nariae
- Höller Nina
- Krainer Marlies
- Schlatzer Christoph
- Schober Lukas
- Schwaberger Bernhard
- Urlesberger Berndt
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- Abstract:
- The transition from intrauterine to extrauterine life is a critical period for neonates. Assessing the cardiovascular transition during this period immediately after birth is crucial but challenging. The present study compares adjusted estimated cardiac output values calculated by the Liljestrand and Zander formula (COest/adj LaZ) with non-invasively measured cardiac output values (CO-bioimpedance) during immediate transition after birth. We performed a secondary outcome analysis of a prospective observational study in preterm and term neonates. Ten and 15 min after birth, arterial blood pressure and heart rate were assessed, and CO-bioimpedance was measured using electrical bioimpedance method (Aesculon monitor, Osypka, Germany). We calculated COest/adj LaZ and compared it to CO-bioimpedance. Further, we performed a correlation analysis. Thirty-two neonates with a median (IQR) gestational age of 37.0 (32.0-39.4) weeks were included. Mean ± SD CO-bioimpedance was 0.62 ± 0.15 l/min, and COest/adj LaZ was calculated to be 0.64 ± 0.10 l/min, whereby both correlated significantly (p = 0.025, r = 0.359) with each other. Conclusion: The present study demonstrates high comparability of COest/adj LaZ and CO-bioimpedance in neonates during immediate transition after birth, suggesting that cardiac output can be derived in a cost-effective and feasible manner if other methods are not available. What is Known: • Echocardiography is considered the gold standard for non-invasive CO evaluation, but its feasibility during the immediate transition period is limited. What is New: • Non-invasive methods such as CO-bioimpedance for cardiac output (CO) measurement and the Liljestrand and Zander (LaZ) formula for estimating CO offer promising alternatives during the immediate transition period.
- Find related publications in this database (using NLM MeSH Indexing)
- Humans - administration & dosage
- Cardiac Output - physiology
- Infant, Newborn - administration & dosage
- Prospective Studies - administration & dosage
- Female - administration & dosage
- Male - administration & dosage
- Electric Impedance - administration & dosage
- Infant, Premature - physiology
- Heart Rate - physiology
- Gestational Age - administration & dosage
- Find related publications in this database (Keywords)
- Cardiac output
- Neonate
- Transition period
- Liljestrand and Zander
- NICOM