Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Direkt zur Navigaton springen.
Direkt zum Inhalt springen.

Navigation/Suche

Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid Stoffw Microb

Baudo, A; Morra, S; Scheipner, L; Jannello, LMI; de, Angelis, M; Siech, C; Touma, N; Goyal, JA; Tian, Z; Acquati, P; Longo, N; Ahyai, S; de, Cobelli, O; Briganti, A; Chun, FKH; Saad, F; Shariat, SF; Carmignani, L; Karakiewicz, PI.
The effect of married status on cancer-specific mortality in nonmetastatic pelvic liposarcoma patients according to sex.
World J Surg. 2024; 48(1):97-103 Doi: 10.1002/wjs.12040
PubMed FullText FullText_MUG

Co-Autor*innen der Med Uni Graz: Ahyai Sascha; Scheipner Lukas
Altmetrics:
Dimensions Citations:
Plum Analytics:
Scite (citation analytics):
Abstract:: BACKGROUND: In nonmetastatic pelvic liposarcoma patients, it is unknown whether married status is associated with better cancer-control outcome defined as cancer-specific mortality (CSM). We addressed this knowledge gap and hypothesized that married status is associated with lower CSM rates in both male and female patients. METHODS: Within the Surveillance, Epidemiology, and End Results database (2000-2020), nonmetastatic pelvic liposarcoma patients were identified. Kaplan-Meier plots and univariable and multivariable Cox regression models (CRMs) predicting CSM according to marital status were used in the overall cohort and in male and female subgroups. RESULTS: Of 1078 liposarcoma patients, 764 (71%) were male and 314 (29%) female. Of 764 male patients, 542 (71%) were married. Conversely, of 314 female patients, 192 (61%) were married. In the overall cohort, 5-year cancer-specific mortality-free survival (CSM-FS) rates were 89% for married versus 83% for unmarried patients (Δ = 6%). In multivariable CRMs, married status did not independently predict lower CSM (hazard ratio [HR]: 0.74, p = 0.06). In males, 5-year CSM-FS rates were 89% for married versus 86% for unmarried patients (Δ = 3%). In multivariable CRMs, married status did not independently predict lower CSM (HR: 0.85, p = 0.4). In females, 5-year CSM-FS rates were 88% for married versus 79% for unmarried patients (Δ = 9%). In multivariable CRMs, married status independently predicted lower CSM (HR: 0.58, p = 0.03). CONCLUSIONS: In nonmetastatic pelvic liposarcoma patients, married status independently predicted lower CSM only in female patients. In consequence, unmarried female patients should ideally require more assistance and more frequent follow-up than their married counterparts.
Find related publications in this database (using NLM MeSH Indexing): Humans - administration & dosage; Male - administration & dosage; Liposarcoma - mortality; Female - administration & dosage; Middle Aged - administration & dosage; Marital Status - statistics & numerical data; Aged - administration & dosage; Pelvic Neoplasms - mortality; Sex Factors - administration & dosage; SEER Program - administration & dosage; Adult - administration & dosage; Retrospective Studies - administration & dosage