Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Smolle, MA; Puchwein, P; Sadoghi, P.
Skin Antisepsis before Surgical Fracture Fixation.
N Engl J Med. 2024; 390(16): 1532-1533.
Doi: 10.1056/NEJMc2403234
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Sadoghi Patrick
- Smolle Maria Anna
- Co-Autor*innen der Med Uni Graz
- Puchwein Paul
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- Abstract:
- To the Editor: In the PREPARE trial conducted by the PREP-IT investigators, Sprague and colleagues (Feb. 1 issue)(1) found a protective effect of skin antisepsis with iodine povacrylex as compared with chlorhexidine gluconate against surgical-site infection in patients undergoing procedures for closed lower limb and pelvic fractures. However, the investigators found no between-group difference in patients undergoing surgery for open fractures. In making this determination, the investigators did not report and consequently adjust for the duration of surgery, a known risk factor for surgical-site infection.(2,3) This omission may serve as an additional explanation for the lack of a significant difference . . .
- Find related publications in this database (using NLM MeSH Indexing)
- Humans - administration & dosage
- Antisepsis - methods
- Skin - microbiology
- Anti-Infective Agents, Local - therapeutic use
- Fracture Fixation - methods
- Preoperative Care - administration & dosage
- Surgical Wound Infection - prevention & control