Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Runtsch, MC; O'Neill, LA.
GOTcha: lncRNA-ACOD1 targets metabolism during viral infection.
Cell Res. 2018; 28(2): 137-138.
Doi: 10.1038/cr.2017.153
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- Führende Autor*innen der Med Uni Graz
- Runtsch Marah
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- Abstract:
- Long-noncoding RNAs (lncRNAs) are emerging as important regulators of cellular processes, but few have been functionally characterized in host-pathogen interactions. A recent report in Science demonstrates a mechanistic role for a novel lncRNA in directly binding an essential metabolic enzyme, glutamic-oxaloacetic transaminase (GOT2); this interaction benefits viral replication via alteration of host metabolism.
- Find related publications in this database (using NLM MeSH Indexing)
- Antiviral Agents - administration & dosage
- Humans - administration & dosage
- Interferons - administration & dosage
- RNA, Long Noncoding - administration & dosage
- Virus Diseases - administration & dosage
- Virus Replication - administration & dosage