Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Runtsch, MC; O'Neill, LAJ.
Pseudomonas Persists by Feeding off Itaconate.
Cell Metab. 2020; 31(6): 1045-1047.
Doi: 10.1016/j.cmet.2020.05.005
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Runtsch Marah
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- Abstract:
- Itaconate is an immunometabolite with anti-inflammatory and anti-microbial properties. Riquelme et al. (2020) demonstrate that pathogenic Pseudomonas aeruginosa drives itaconate production by macrophages, which it then uses as a carbon source for biofilm formation, allowing it to persist during infection and suppress inflammation.
- Find related publications in this database (using NLM MeSH Indexing)
- Biofilms - administration & dosage
- Pseudomonas - administration & dosage
- Pseudomonas aeruginosa - administration & dosage
- Succinates - administration & dosage