Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Dimai, HP; Obermayer-Pietsch, B.
Biochemical Markers of Bone Turnover in the Light of Bone Relevant Diseases
OSTEOLOGIE. 2023; 32(04): 251-258.
Doi: 10.1055/a-2189-6143
Web of Science
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Dimai Hans Peter
- Co-Autor*innen der Med Uni Graz
- Obermayer-Pietsch Barbara
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Bone is a living tissue characterised by a lifelong turnover process. The latter can be quantified by measurement of specific circulating substrates which reflect either bone formation or bone resorption, and thus are also referred to as biochemical markers of bone turnover, or simply bone turnover markers. They may either be secreted directly by bone cells, such as the alkaline phosphatase (ALP), osteocalcin (OC) and the tartrate-resistant acid phosphatase (TRAP), or released from bone matrix during bone degradation, such as the C-terminal and N-terminal telopeptide of type-1 collagen (CTX, NTX). In the years past, a considerable number of diseases have been identified to affect bone metabolism with the consequence of an increase or decrease of these markers. Accordingly, such diseases can be classified as either associated with high or low bone turnover. Measurement of and information about these circulating markers may support decision making when treatment is considered. However, in general their added-value remains low regarding the diagnosis of such diseases.
- Find related publications in this database (Keywords)
- biochemical
- markers
- bone
- turnover