Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Disma, N; Engelhardt, T; Hansen, TG; de, Graaff, JC; Virag, K; Habre, W; NECTARINE Group of the European Society of Anaesthesiology and Intensive.
Neonates undergoing pyloric stenosis repair are at increased risk of difficult airway management: secondary analysis of the NEonate and Children audiT of Anaesthesia pRactice IN Europe.
Br J Anaesth. 2022; 129(5): 734-739.
Doi: 10.1016/j.bja.2022.07.041
Web of Science
PubMed
FullText
FullText_MUG
- Study Group Members Med Uni Graz:
- Edelmann Isolde Maria
- Eger Johannes
- Heschl Stefan
- Messerer Brigitte
- Vittinghoff Maria
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- BACKGROUND: Hypertrophic pyloric stenosis in otherwise healthy neonates frequently requires urgent surgical procedure but anaesthesia care may result in respiratory complications, such as hypoxaemia, pulmonary aspiration of gastric contents, and postoperative apnoea. The primary aim was to study whether or not the incidence of difficult airway management and of hypoxaemia in neonates undergoing pyloric stenosis repair was higher than that in neonates undergoing other surgeries. METHODS: Data on neonates and infants undergoing anaesthesia and surgery for pyloric stenosis were extracted from the NEonate and Children audiT of Anesthesia pRactice In Europe (NECTARINE) database, for secondary analysis. RESULTS: We identified 310 infants who had anaesthesia for surgery for pyloric stenosis. Difficult airway management (more than two attempts at laryngoscopy) was higher in children with pyloric stenosis when compared with the entire NECTARINE cohort (7.9% [95% confidence interval {CI}, 5.22-11.53] vs 4.4% [95% CI, 1.99-6.58]; relative risk [RR]=1.81 [95% CI, 1.21-2.69]; P=0.004), whereas transient hypoxaemia with oxygen saturation <90% was comparable between the two cohorts. Postoperative complications occurred in 16 children (5.6%) within the 30-day follow-up. No mortality was reported at 30 and 90 days. CONCLUSIONS: Children undergoing surgery for pyloric stenosis had a higher incidence of difficult intubation compared with the entire NECTARINE cohort. CLINICAL TRIAL REGISTRATION: NCT02350348.
- Find related publications in this database (using NLM MeSH Indexing)
- Child - administration & dosage
- Humans - administration & dosage
- Infant - administration & dosage
- Infant, Newborn - administration & dosage
- Airway Management - methods
- Anesthesia - adverse effects
- Europe - epidemiology
- Hypoxia - epidemiology, etiology
- Intubation, Intratracheal - adverse effects, methods
- Pyloric Stenosis, Hypertrophic - surgery
- Find related publications in this database (Keywords)
- airway management
- complications
- difficult airway
- neonatal anaesthesia
- pyloric stenosis
- tracheal intubation