Medizinische Universität Graz - Research portal
Selected Publication:
Arikan, G; Gucer, F; Schöll, W; Weiss, PAM.
Preterm Labor During Oral Magnesium Supplementation in Uncomplicated Pregnancies
GEBURTSH FRAUENHEILK 1997 57: 491-495.
Doi: 10.1055/s-2007-1023124
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- Co-authors Med Uni Graz
- Schöll Wolfgang
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- Abstract:
- The null hypothesis of this study was that oral magnesium supplementation would not affect the incidence of preterm contractions, preterm labour and associated neonatal complications. 530 women with low-risk pregnancies were recruited until the 18(th) week of gestation and assigned to receive 15 mmol magnesium citrate once daily PO (n=265) or no supplementation (n=265). 240 patients and 250 controls completed the study. The patients receiving magnesium had a significantly lower rate of hospitalisation due to threatened preterm labour (6.6% vs. 12.0%, p < 0.05), significantly higher birth weight (3377 +/- 503 vs. 3287 +/- 477 g, p < 0.05) and the rates of preterm labour and birth weight < 2500 g were lower in the patients receiving magnesium, but not significantly so (4.6% vs. 8.0% and 2.9% vs. 4.8%, respectively). The rate of admissions to the neonatal care unit was 1.6% in both groups. The results show that a daily oral supplementation of 15 mmol (365 mg) magnesium exercises a positive influence on the rate of hospitalisations due to threatened preterm labour, and also on the birth weight.