Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Baudo, A; Morra, S; Scheipner, L; Jannello, LMI; de Angelis, M; Siech, C; Touma, N; Goyal, JA; Tian, Z; Acquati, P; Longo, N; Ahyai, S; de Cobelli, O; Briganti, A; Chun, FKH; Saad, F; Shariat, SF; Carmignani, L; Karakiewicz, PI.
The effect of married status on cancer-specific mortality in nonmetastatic pelvic liposarcoma patients according to sex
WORLD J SURG. 2023;
Doi: 10.1002/wjs.12040
Web of Science
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- Co-Autor*innen der Med Uni Graz
- Ahyai Sascha
- Scheipner Lukas
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- Abstract:
- BackgroundIn nonmetastatic pelvic liposarcoma patients, it is unknown whether married status is associated with better cancer-control outcome defined as cancer-specific mortality (CSM). We addressed this knowledge gap and hypothesized that married status is associated with lower CSM rates in both male and female patients.MethodsWithin the Surveillance, Epidemiology, and End Results database (2000-2020), nonmetastatic pelvic liposarcoma patients were identified. Kaplan-Meier plots and univariable and multivariable Cox regression models (CRMs) predicting CSM according to marital status were used in the overall cohort and in male and female subgroups.ResultsOf 1078 liposarcoma patients, 764 (71%) were male and 314 (29%) female. Of 764 male patients, 542 (71%) were married. Conversely, of 314 female patients, 192 (61%) were married. In the overall cohort, 5-year cancer-specific mortality-free survival (CSM-FS) rates were 89% for married versus 83% for unmarried patients (Delta = 6%). In multivariable CRMs, married status did not independently predict lower CSM (hazard ratio [HR]: 0.74, p = 0.06). In males, 5-year CSM-FS rates were 89% for married versus 86% for unmarried patients (Delta = 3%). In multivariable CRMs, married status did not independently predict lower CSM (HR: 0.85, p = 0.4). In females, 5-year CSM-FS rates were 88% for married versus 79% for unmarried patients (Delta = 9%). In multivariable CRMs, married status independently predicted lower CSM (HR: 0.58, p = 0.03).ConclusionsIn nonmetastatic pelvic liposarcoma patients, married status independently predicted lower CSM only in female patients. In consequence, unmarried female patients should ideally require more assistance and more frequent follow-up than their married counterparts.
- Find related publications in this database (Keywords)
- cancer-specific mortality
- marital status
- pelvic liposarcoma