Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Lisney, AR; Leitsmann, C; Strauß, A; Meller, B; Bucerius, JA; Sahlmann, CO.
The Role of PSMA PET/CT in the Primary Diagnosis and Follow-Up of Prostate Cancer-A Practical Clinical Review.
Cancers (Basel). 2022; 14(15):
Doi: 10.3390/cancers14153638
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- Co-Autor*innen der Med Uni Graz
- Bucerius Jan Alexander
- Leitsmann Conrad
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- Abstract:
- The importance of PSMA PET/CT in both primary diagnostics and prostate cancer recurrence has grown steadily since its introduction more than a decade ago. Over the past years, a vast amount of data have been published on the diagnostic accuracy and the impact of PSMA PET/CT on patient management. Nevertheless, a large heterogeneity between studies has made reaching a consensus difficult; this review aims to provide a comprehensive clinical review of the available scientific literature, covering the currently known data on physiological and pathological PSMA expression, influencing factors, the differences and pitfalls of various tracers, as well as the clinical implications in initial TNM-staging and in the situation of biochemical recurrence. This review has the objective of providing a practical clinical overview of the advantages and disadvantages of the examination in various clinical situations and the body of knowledge available, as well as open questions still requiring further research.
- Find related publications in this database (Keywords)
- PSMA PET
- CT
- prostate cancer
- prostate-specific membrane antigen
- PSMA
- PET
- CT
- PET