Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Obermayer-Pietsch, B; Foessl, I.
Monitoring of Bone Turnover During Pharmacological Treatment
OSTEOLOGIE. 2023;
Doi: 10.1055/a-2175-8651
Web of Science
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- Führende Autor*innen der Med Uni Graz
- Obermayer-Pietsch Barbara
- Co-Autor*innen der Med Uni Graz
- Fößl Ines
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- Abstract:
- Osteoporosis is per se a chronic disease, requiring non-pharmacological interventions such as nutritional and training adaptations, but also a long-term use of bone-specific pharmacological treatments, including antiresorptive and/ or osteoanabolic or even dual approaches. Imaging options such as bone density measurements, risk algorithms and the assessment of bone turnover are necessary for the monitoring of such therapies. While bone density measurements during monitoring of treatment are only useful in more than annual intervals due to the slow reaction of bone structure and density to therapeutic interventions, lab-based analyses of bone turnover are surrogate markers for individual "flash-lights" of bone metabolism and easy-to-access information in shorter intervals of choice. This review aims to discuss markers of bone metabolism in view of long-term strategies, combination and sequential therapy and the management of drug holidays as a tool to monitor individual reactions and needs of pharmacological therapy options. Specific patient groups or secondary forms of osteoporosis will be discussed as well as new developments for the future monitoring of patients with osteoporosis.
- Find related publications in this database (Keywords)
- Osteoporosis
- pharmacological therapy
- monitoring
- bone turnover markers