Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Quaglino, P; Pimpinelli, N; Zinzani, PL; Paulli, M; Pileri, S; Berti, E; Cerroni, L; Guitart, J; Kim, YH; Rupoli, S; Santucci, M; Simontacchi, G; Vermeer, M; Hoppe, R; Pro, B; Swerdlow, SH; Barosi, G.
Identifying and addressing unmet clinical needs in primary cutaneous B-cell lymphoma: A consensus-based paper from an ad-hoc international panel
HEMATOL ONCOL. 2023;
Doi: 10.1002/hon.3215
Web of Science
PubMed
FullText
FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Cerroni Lorenzo
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- Abstract:
- Primary cutaneous B-cell lymphomas (PCBCLs) are lymphoproliferative disorders that appear on the skin without evidence of extracutaneous manifestations at the time of diagnosis. There is a lack of evidence-based guidelines for their clinical management due to the availability of very few large scale studies and controlled clinical trials. Here we present and discuss a series of major unmet clinical needs (UCNs) in the management of PCBCLs by a panel of 16 experts involved in research and clinical practice of PCBCL. The Panel produced recommendations on the appropriateness of the clinical decisions concerning the identified clinical needs and proposed research for improving the knowledge needed to solve them. Recommendations and proposals were achieved by multiple-step formalized procedures to reach a consensus after a comprehensive analysis of the scientific literature. Recommendations and proposals lay in the domain of classification uncertainties of PCBCL, optimization of diagnosis, optimization of prognosis, optimization of staging and critical issues on therapeutic strategies with particular focus on new treatments. These recommendations are intended for use not only by experts but above all by dermatologists and hematologists with limited experience in the field of PCBCLs as well as general practitioners.
- Find related publications in this database (Keywords)
- CBCL DIAGNOSIS
- CBCL PROGNOSIS
- CBCL TREATMENT
- clinical needs
- primary cutaneous B-cell lymphoma